The API provides a wide range of detailed disease information, facilitating access to key data for medical analysis and applications. From specific related genes to genetic variants and associated phenotypes, this API becomes an invaluable tool for understanding and addressing various medical conditions.
At its core, the API provides access to comprehensive disease data, enabling the querying of information such as genes linked to a particular disease, genetic variants identified in association with the condition, and relevant clinical phenotypes. This information is essential for researchers studying the genetic basis of diseases, as it provides detailed insight into how certain genes and their variants may influence predisposition to or development of a specific disease.
A highlight of the API is its ability to easily integrate with existing applications and systems in healthcare and biomedical research. This allows developers to create custom tools that use the API data to improve the diagnosis, treatment and understanding of complex diseases.
In short, the API not only provides access to detailed and accurate data on diseases, genes and genetic variants, but also stands out for its ability to support scientific research, medical innovation and continuous improvement of evidence-based healthcare. Its versatility and robustness make it an essential tool in the arsenal of any practitioner or researcher seeking to understand and address the complexities of disease from an advanced genomic and clinical perspective.
It will receive a parameter and provide you with a JSON.
Besides the number of API calls, there is no other limitation.
To use this endpoint you must indicate the name of a disease in the parameter.
| Object | Description |
|---|---|
q |
[Required] |
Continue with Google
Continue with Github
{"took":2,"total":711,"max_score":7.934078,"hits":[{"_id":"MONDO:0011361","_score":7.934078,"ctd":{"omim":"603688","pathway_related_to_disease":[{"inference_gene_symbol":"EPHB2","kegg_pathway_id":"hsa04360","pathway_name":"Axon guidance","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Developmental Biology","react_pathway_id":"R-HSA-1266738","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPH-Ephrin signaling","react_pathway_id":"R-HSA-2682334","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"L1CAM interactions","react_pathway_id":"R-HSA-373760","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPHB-mediated forward signaling","react_pathway_id":"R-HSA-3928662","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Ephrin signaling","react_pathway_id":"R-HSA-3928664","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPH-ephrin mediated repulsion of cells","react_pathway_id":"R-HSA-3928665","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Axon guidance","react_pathway_id":"R-HSA-422475","source":"CTD"}]},"disgenet":{"_license":"https://creativecommons.org/licenses/by/4.0/","genes_related_to_disease":[{"DPI":0.846,"DSI":0.374,"gene_id":2048,"gene_name":"EPHB2","score":0.4,"source":"CLINVAR"},{"DPI":0.846,"DSI":0.374,"gene_id":2048,"gene_name":"EPHB2","score":0.4,"source":"CTD_human"}],"variants_related_to_disease":[{"DSI":1.0,"chrom":"1","pos":22907980,"rsid":"rs121912582","score":0.7,"source":"CLINVAR"},{"DPI":0.08,"DSI":0.882,"chrom":"1","pos":22913757,"rsid":"rs76826147","score":0.7,"source":"CLINVAR"}],"xrefs":{"disease_name":"PROSTATE CANCER/BRAIN CANCER SUSCEPTIBILITY (finding)","mondo":"MONDO:0011361","omim":"603688","umls":"C1863600"}},"hpo":{"disease_name":"Prostate cancer/brain cancer susceptibility","omim":"603688","phenotype_related_to_disease":[{"biocuration":[{"date":"2013-01-14","name":"HPO:skoehler"}],"evidence":"IEA","hpo_id":"HP:0100006","omim_refs":["OMIM:603688"],"original_disease_id":"OMIM:603688"},{"biocuration":[{"date":"2013-01-09","name":"HPO:skoehler"}],"evidence":"IEA","hpo_id":"HP:0012125","omim_refs":["OMIM:603688"],"original_disease_id":"OMIM:603688"}]},"mondo":{"ancestors":["MONDO:0015356","MONDO:0002254","MONDO:0700096","MONDO:0042489","MONDO:0021058","MONDO:0000001","MONDO:0020573","MONDO:0023370","MONDO:0045024","MONDO:0003847"],"excluded_subClassOf":{"mondo":["MONDO:0008315"]},"has_material_basis_in_germline_mutation_in":{"http":["http://identifiers.org/hgnc/3393"]},"label":"prostate cancer/brain cancer susceptibility","mondo":"MONDO:0011361","parents":["MONDO:0015356"],"predisposes_towards":{"mondo":["MONDO:0001657"]},"synonym":{"exact":["prostate cancer/brain cancer susceptibility","prostate cancer/brain cancer susceptibility, somatic"],"related":["Capb","Pcbc"]},"xrefs":{"omim":["603688"]}}},{"_id":"MONDO:0018502","_score":7.331036,"mondo":{"ancestors":["MONDO:0004992","MONDO:0004298","MONDO:0005070","MONDO:0004993","MONDO:0001056","MONDO:0004335","MONDO:0000001","MONDO:0023370","MONDO:0045024","MONDO:0003847","MONDO:0021085","MONDO:0006181","MONDO:0002516","MONDO:0021223","MONDO:0005626","MONDO:0700096","MONDO:0004950"],"children":["MONDO:0006226","MONDO:0007648","MONDO:0017790","MONDO:0100256"],"definition":"Hereditary gastric cancer refers to the occurrence of gastric cancer in a familial context and is described as two or more cases of gastric cancer in first or second degree relatives with at least one case diagnosed before the age of 50. Familial clustering is observed in 10% of all cases of gastric cancer, and includes hereditary diffuse gastric cancer (early onset diffuse-type gastric cancer), gastric adenocarcinoma and proximal polyposis of the stomach and familial intestinal gastric cancer (familial clustering of intestinal type gastric adenocarcinoma). Hereditary gastric cancer can also occur in other hereditary cancer syndromes such as Lynch syndrome, Li-Fraumeni syndrome, familial adenomatous polyposis and juvenile polyposis syndrome. [Orphanet:423776]","descendants":["MONDO:0007648","MONDO:0100256","MONDO:0017790","MONDO:0006226"],"has_characteristic":{"mondo":["MONDO:0021136"]},"label":"hereditary gastric cancer","mondo":"MONDO:0018502","parents":["MONDO:0003847","MONDO:0004950"],"synonym":{"exact":["hereditary cancer of stomach","hereditary gastric cancer"]},"xrefs":{"gard":["21758"],"orphanet":["423776"]}}},{"_id":"MONDO:0001060","_score":7.2445354,"disease_ontology":{"_license":"https://github.com/DiseaseOntology/HumanDiseaseOntology/blob/master/DO_LICENSE.txt","ancestors":["DOID:10534","DOID:305","DOID:3717","DOID:77","DOID:7","DOID:76","DOID:299","DOID:0050686","DOID:4","DOID:3119","DOID:0050687","DOID:14566","DOID:5517","DOID:162"],"children":[],"def":"","descendants":[],"doid":"DOID:10541","name":"microinvasive gastric cancer","parents":["DOID:3717"],"synonyms":{"exact":["early gastric cancer","Surface gastric cancer"]},"xrefs":{"ncit":"C27131","snomedct_us_2023_03_01":"276809004","umls_cui":"C0349530"}},"disgenet":{"_license":"https://creativecommons.org/licenses/by/4.0/","genes_related_to_disease":[{"DPI":0.885,"DSI":0.429,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":174,"gene_name":"AFP","pubmed":[29121872],"score":0.01,"source":"BEFREE"},{"DPI":0.962,"DSI":0.373,"EI":1.0,"YearFinal":2016,"YearInitial":2014,"gene_id":324,"gene_name":"APC","pubmed":[27514024,24272205],"score":0.02,"source":"BEFREE"},{"DPI":0.808,"DSI":0.502,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":387,"gene_name":"RHOA","pubmed":[28624843],"score":0.01,"source":"BEFREE"},{"DPI":0.923,"DSI":0.344,"EI":1.0,"YearFinal":2014,"YearInitial":2014,"gene_id":595,"gene_name":"CCND1","pubmed":[25202078],"score":0.01,"source":"BEFREE"},{"DPI":0.423,"DSI":0.666,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":618,"gene_name":"BCYRN1","pubmed":[29039538],"score":0.01,"source":"BEFREE"},{"DPI":0.731,"DSI":0.459,"EI":1.0,"YearFinal":2008,"YearInitial":2008,"gene_id":864,"gene_name":"RUNX3","pubmed":[18097595],"score":0.01,"source":"BEFREE"},{"DPI":0.962,"DSI":0.363,"EI":1.0,"YearFinal":2019,"YearInitial":2016,"gene_id":960,"gene_name":"CD44","pubmed":[27923017,30913874,25779358],"score":0.03,"source":"BEFREE"},{"DPI":0.808,"DSI":0.401,"EI":1.0,"YearFinal":2010,"YearInitial":2010,"gene_id":999,"gene_name":"CDH1","pubmed":[20063069],"score":0.01,"source":"BEFREE"},{"DPI":0.769,"DSI":0.458,"EI":1.0,"YearFinal":2019,"YearInitial":2019,"gene_id":1045,"gene_name":"CDX2","pubmed":[31354341],"score":0.01,"source":"BEFREE"},{"DPI":0.846,"DSI":0.42,"EI":1.0,"YearFinal":2018,"YearInitial":2017,"gene_id":1048,"gene_name":"CEACAM5","pubmed":[29121872,29742692],"score":0.02,"source":"BEFREE"},{"DPI":0.731,"DSI":0.494,"EI":1.0,"YearFinal":2018,"YearInitial":2017,"gene_id":1084,"gene_name":"CEACAM3","pubmed":[29121872,29742692],"score":0.02,"source":"BEFREE"},{"DPI":0.769,"DSI":0.494,"EI":1.0,"YearFinal":2018,"YearInitial":2017,"gene_id":1087,"gene_name":"CEACAM7","pubmed":[29121872,29742692],"score":0.02,"source":"BEFREE"},{"DPI":0.808,"DSI":0.446,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":1268,"gene_name":"CNR1","pubmed":[27271924],"score":0.01,"source":"BEFREE"},{"DPI":0.846,"DSI":0.4,"EI":1.0,"YearFinal":2018,"YearInitial":2018,"gene_id":1351,"gene_name":"COX8A","pubmed":[30128004],"score":0.01,"source":"BEFREE"},{"DPI":0.615,"DSI":0.558,"EI":1.0,"YearFinal":2012,"YearInitial":2012,"gene_id":1365,"gene_name":"CLDN3","pubmed":[22290341],"score":0.01,"source":"BEFREE"},{"DPI":0.808,"DSI":0.494,"EI":1.0,"YearFinal":2012,"YearInitial":2012,"gene_id":1366,"gene_name":"CLDN7","pubmed":[22290341],"score":0.01,"source":"BEFREE"},{"DPI":0.846,"DSI":0.488,"EI":1.0,"YearFinal":2018,"YearInitial":2018,"gene_id":1371,"gene_name":"CPOX","pubmed":[29425880],"score":0.01,"source":"BEFREE"},{"DPI":0.923,"DSI":0.328,"EI":1.0,"YearFinal":2005,"YearInitial":2005,"gene_id":1636,"gene_name":"ACE","pubmed":[16365022],"score":0.01,"source":"BEFREE"},{"DPI":0.885,"DSI":0.426,"EI":1.0,"YearFinal":2019,"YearInitial":2019,"gene_id":1666,"gene_name":"DECR1","pubmed":[31370714],"score":0.01,"source":"BEFREE"},{"DPI":0.885,"DSI":0.295,"EI":1.0,"YearFinal":2015,"YearInitial":2015,"gene_id":1956,"gene_name":"EGFR","pubmed":[25593477],"score":0.01,"source":"BEFREE"},{"DPI":0.923,"DSI":0.328,"EI":1.0,"YearFinal":2018,"YearInitial":2015,"gene_id":2064,"gene_name":"ERBB2","pubmed":[30120594,25593477],"score":0.02,"source":"BEFREE"},{"DPI":0.615,"DSI":0.656,"EI":1.0,"YearFinal":2019,"YearInitial":2017,"gene_id":2098,"gene_name":"ESD","pubmed":[31382963,30725253,28378078,30298447],"score":0.04,"source":"BEFREE"},{"DPI":0.692,"DSI":0.588,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":2168,"gene_name":"FABP1","pubmed":[27884752],"score":0.01,"source":"BEFREE"},{"DPI":0.846,"DSI":0.474,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":2194,"gene_name":"FASN","pubmed":[27884752],"score":0.01,"source":"BEFREE"},{"DPI":0.808,"DSI":0.485,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":2520,"gene_name":"GAST","pubmed":[28072871],"score":0.01,"source":"BEFREE"},{"DPI":0.808,"DSI":0.489,"EI":1.0,"YearFinal":2019,"YearInitial":2019,"gene_id":2744,"gene_name":"GLS","pubmed":[30485682],"score":0.01,"source":"BEFREE"},{"DPI":0.577,"DSI":0.686,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":3004,"gene_name":"GZMM","pubmed":[28977792],"score":0.01,"source":"BEFREE"},{"DPI":0.885,"DSI":0.374,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":3082,"gene_name":"HGF","pubmed":[28595915],"score":0.01,"source":"BEFREE"},{"DPI":0.769,"DSI":0.476,"EI":1.0,"YearFinal":2015,"YearInitial":2015,"gene_id":3490,"gene_name":"IGFBP7","pubmed":[26043748],"score":0.01,"source":"BEFREE"},{"DPI":0.923,"DSI":0.373,"EI":1.0,"YearFinal":2004,"YearInitial":2004,"gene_id":3557,"gene_name":"IL1RN","pubmed":[15570075],"score":0.01,"source":"BEFREE"},{"DPI":0.962,"DSI":0.248,"EI":1.0,"YearFinal":2001,"YearInitial":20...
curl --location --request GET 'https://zylalabs.com/api/4424/diseases+information+api/5437/disease?q=cancer' --header 'Authorization: Bearer YOUR_API_KEY'
To use this endpoint you must specify a Mondo ID in the parameter.
For example: MONDO:0011361
You will get this ID from the Disease endpoint.
{"_id":"MONDO:0011361","_version":1,"ctd":{"omim":"603688","pathway_related_to_disease":[{"inference_gene_symbol":"EPHB2","kegg_pathway_id":"hsa04360","pathway_name":"Axon guidance","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Developmental Biology","react_pathway_id":"R-HSA-1266738","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPH-Ephrin signaling","react_pathway_id":"R-HSA-2682334","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"L1CAM interactions","react_pathway_id":"R-HSA-373760","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPHB-mediated forward signaling","react_pathway_id":"R-HSA-3928662","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Ephrin signaling","react_pathway_id":"R-HSA-3928664","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPH-ephrin mediated repulsion of cells","react_pathway_id":"R-HSA-3928665","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Axon guidance","react_pathway_id":"R-HSA-422475","source":"CTD"}]},"disgenet":{"_license":"https://creativecommons.org/licenses/by/4.0/","genes_related_to_disease":[{"DPI":0.846,"DSI":0.374,"gene_id":2048,"gene_name":"EPHB2","score":0.4,"source":"CLINVAR"},{"DPI":0.846,"DSI":0.374,"gene_id":2048,"gene_name":"EPHB2","score":0.4,"source":"CTD_human"}],"variants_related_to_disease":[{"DSI":1.0,"chrom":"1","pos":22907980,"rsid":"rs121912582","score":0.7,"source":"CLINVAR"},{"DPI":0.08,"DSI":0.882,"chrom":"1","pos":22913757,"rsid":"rs76826147","score":0.7,"source":"CLINVAR"}],"xrefs":{"disease_name":"PROSTATE CANCER/BRAIN CANCER SUSCEPTIBILITY (finding)","mondo":"MONDO:0011361","omim":"603688","umls":"C1863600"}},"hpo":{"disease_name":"Prostate cancer/brain cancer susceptibility","omim":"603688","phenotype_related_to_disease":[{"biocuration":[{"date":"2013-01-14","name":"HPO:skoehler"}],"evidence":"IEA","hpo_id":"HP:0100006","omim_refs":["OMIM:603688"],"original_disease_id":"OMIM:603688"},{"biocuration":[{"date":"2013-01-09","name":"HPO:skoehler"}],"evidence":"IEA","hpo_id":"HP:0012125","omim_refs":["OMIM:603688"],"original_disease_id":"OMIM:603688"}]},"mondo":{"ancestors":["MONDO:0015356","MONDO:0002254","MONDO:0700096","MONDO:0042489","MONDO:0021058","MONDO:0000001","MONDO:0020573","MONDO:0023370","MONDO:0045024","MONDO:0003847"],"excluded_subClassOf":{"mondo":["MONDO:0008315"]},"has_material_basis_in_germline_mutation_in":{"http":["http://identifiers.org/hgnc/3393"]},"label":"prostate cancer/brain cancer susceptibility","mondo":"MONDO:0011361","parents":["MONDO:0015356"],"predisposes_towards":{"mondo":["MONDO:0001657"]},"synonym":{"exact":["prostate cancer/brain cancer susceptibility","prostate cancer/brain cancer susceptibility, somatic"],"related":["Capb","Pcbc"]},"xrefs":{"omim":["603688"]}}}
curl --location --request GET 'https://zylalabs.com/api/4424/diseases+information+api/5439/disease+by+id&ID=Required' --header 'Authorization: Bearer YOUR_API_KEY'
After signing up, every developer is assigned a personal API access key, a unique combination of letters and digits provided to access to our API endpoint. To authenticate with the Diseases Information API REST API, simply include your bearer token in the Authorization header.
| Header | Description |
|---|---|
Authorization
|
[Required] Should be Bearer access_key. See "Your API Access Key" above when you are subscribed. |
No long term commitments. One click upgrade/downgrade or cancellation. No questions asked.
Diseases Information API provides structured data and information on various diseases, including genetic factors, associated genes, clinical manifestations and related pathways.
Zyla provides a wide range of integration methods for almost all programming languages. You can use these codes to integrate with your project as you need.
There are different plans to suit all tastes, including a free trial for a small number of requests, but your rate is limited to avoid abuse of the service.
This API is essential because it allows users to obtain detailed and up-to-date information on a wide range of diseases, including genetic data, associated genes, variants, clinical data and relevant pathways.
To use this API, users must indicate the name of a disease.
Zyla API Hub is, in other words, an API MarketPlace. An all-in-one solution for your developing needs. You will be accessing our extended list of APIs with only your user. Also, you won't need to worry about storing API keys, only one API key for all our products is needed.
Prices are listed in USD. We accept all major debit and credit cards. Our payment system uses the latest security technology and is powered by Stripe, one of the world’s most reliable payment companies. If you have any trouble with paying by card, just contact us at [email protected]
Sometimes depending on the bank's fraud protection settings, a bank will decline the validation charge we make when we attempt to be sure a card is valid. We recommend first contacting your bank to see if they are blocking our charges. If more help is needed, please contact [email protected] and our team will investigate further
Prices are based on a recurring monthly subscription depending on the plan selected — plus overage fees applied when a developer exceeds a plan’s quota limits. In this example, you'll see the base plan amount as well as a quota limit of API requests. Be sure to notice the overage fee because you will be charged for each additional request.
Zyla API Hub works on a recurring monthly subscription system. Your billing cycle will start the day you purchase one of the paid plans, and it will renew the same day of the next month. So be aware to cancel your subscription beforehand if you want to avoid future charges.
Just go to the pricing page of that API and select the plan that you want to upgrade to. You will only be charged the full amount of that plan, but you will be enjoying the features that the plan offers right away.
Yes, absolutely. If you want to cancel your plan, simply go to your account and cancel on the Billing page. Upgrades, downgrades, and cancellations are immediate.
You can contact us through our chat channel to receive immediate assistance. We are always online from 9 am to 6 pm (GMT+1). If you reach us after that time, we will be in contact when we are back. Also you can contact us via email to [email protected]
Service Level:
100%
Response Time:
0ms
Service Level:
100%
Response Time:
3,388ms
Service Level:
100%
Response Time:
3,042ms
Service Level:
100%
Response Time:
397ms
Service Level:
100%
Response Time:
836ms
Service Level:
100%
Response Time:
1,697ms
Service Level:
100%
Response Time:
3,016ms
Service Level:
100%
Response Time:
1,005ms
Service Level:
100%
Response Time:
347ms
Service Level:
100%
Response Time:
2,254ms
Service Level:
100%
Response Time:
709ms
Service Level:
89%
Response Time:
1,156ms
Service Level:
100%
Response Time:
1,444ms
Service Level:
100%
Response Time:
1,751ms
Service Level:
100%
Response Time:
1,155ms
Service Level:
100%
Response Time:
1,287ms
Service Level:
100%
Response Time:
578ms
