La API proporciona una amplia gama de información detallada sobre enfermedades, facilitando el acceso a datos clave para el análisis médico y aplicaciones. Desde genes relacionados específicos hasta variantes genéticas y fenotipos asociados, esta API se convierte en una herramienta invaluable para comprender y abordar diversas condiciones médicas.
En su núcleo, la API proporciona acceso a datos completos sobre enfermedades, permitiendo la consulta de información como genes vinculados a una enfermedad particular, variantes genéticas identificadas en asociación con la condición y fenotipos clínicos relevantes. Esta información es esencial para los investigadores que estudian la base genética de las enfermedades, ya que proporciona una visión detallada de cómo ciertos genes y sus variantes pueden influir en la predisposición o el desarrollo de una enfermedad específica.
Un aspecto destacado de la API es su capacidad para integrarse fácilmente con aplicaciones y sistemas existentes en el cuidado de la salud y la investigación biomédica. Esto permite a los desarrolladores crear herramientas personalizadas que utilizan los datos de la API para mejorar el diagnóstico, tratamiento y comprensión de enfermedades complejas.
En resumen, la API no solo proporciona acceso a datos detallados y precisos sobre enfermedades, genes y variantes genéticas, sino que también se destaca por su capacidad para apoyar la investigación científica, la innovación médica y la mejora continua de la atención médica basada en evidencia. Su versatilidad y robustez la convierten en una herramienta esencial en el arsenal de cualquier profesional o investigador que busque comprender y abordar las complejidades de la enfermedad desde una perspectiva genómica y clínica avanzada.
Recibirá un parámetro y le proporcionará un JSON.
Además del número de llamadas a la API, no hay otra limitación.
Para utilizar este punto final, debe indicar el nombre de una enfermedad en el parámetro.
Enfermedad - Características del Endpoint
Objeto | Descripción |
---|---|
q |
[Requerido] |
{"took":16,"total":724,"max_score":7.9725885,"hits":[{"_id":"MONDO:0011361","_score":7.9725885,"ctd":{"omim":"603688","pathway_related_to_disease":[{"inference_gene_symbol":"EPHB2","kegg_pathway_id":"hsa04360","pathway_name":"Axon guidance","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Developmental Biology","react_pathway_id":"R-HSA-1266738","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPH-Ephrin signaling","react_pathway_id":"R-HSA-2682334","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"L1CAM interactions","react_pathway_id":"R-HSA-373760","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPHB-mediated forward signaling","react_pathway_id":"R-HSA-3928662","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Ephrin signaling","react_pathway_id":"R-HSA-3928664","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPH-ephrin mediated repulsion of cells","react_pathway_id":"R-HSA-3928665","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Axon guidance","react_pathway_id":"R-HSA-422475","source":"CTD"}]},"disgenet":{"_license":"https://creativecommons.org/licenses/by/4.0/","genes_related_to_disease":[{"DPI":0.846,"DSI":0.374,"gene_id":2048,"gene_name":"EPHB2","score":0.4,"source":"CLINVAR"},{"DPI":0.846,"DSI":0.374,"gene_id":2048,"gene_name":"EPHB2","score":0.4,"source":"CTD_human"}],"variants_related_to_disease":[{"DSI":1.0,"chrom":"1","pos":22907980,"rsid":"rs121912582","score":0.7,"source":"CLINVAR"},{"DPI":0.08,"DSI":0.882,"chrom":"1","pos":22913757,"rsid":"rs76826147","score":0.7,"source":"CLINVAR"}],"xrefs":{"disease_name":"PROSTATE CANCER/BRAIN CANCER SUSCEPTIBILITY (finding)","mondo":"MONDO:0011361","omim":"603688","umls":"C1863600"}},"hpo":{"disease_name":"Prostate cancer/brain cancer susceptibility","omim":"603688","phenotype_related_to_disease":[{"biocuration":{"date":"2013-01-14","name":"HPO:skoehler"},"evidence":"IEA","hpo_id":"HP:0100006","omim_refs":"OMIM:603688","original_disease_id":"OMIM:603688"},{"biocuration":{"date":"2013-01-09","name":"HPO:skoehler"},"evidence":"IEA","hpo_id":"HP:0012125","omim_refs":"OMIM:603688","original_disease_id":"OMIM:603688"}]},"mondo":{"ancestors":["MONDO:0003847","MONDO:0020573","MONDO:0023370","MONDO:0021058","MONDO:0700096","MONDO:0002254","MONDO:0045024","MONDO:0042489","MONDO:0015356","MONDO:0000001"],"excluded_subClassOf":{"mondo":["MONDO:0008315"]},"has_material_basis_in_germline_mutation_in":{"http":["http://identifiers.org/hgnc/3393"]},"label":"prostate cancer/brain cancer susceptibility","mondo":"MONDO:0011361","parents":["MONDO:0015356"],"predisposes_towards":{"mondo":["MONDO:0001657"]},"synonym":{"exact":["prostate cancer/brain cancer susceptibility","prostate cancer/brain cancer susceptibility, somatic"],"related":["Capb","Pcbc"]},"xrefs":{"medgen":["400334"],"omim":["603688"],"umls":["C1863600"]}}},{"_id":"MONDO:0018502","_score":7.36427,"mondo":{"ancestors":["MONDO:0005070","MONDO:0021223","MONDO:0700096","MONDO:0001056","MONDO:0004992","MONDO:0021085","MONDO:0005626","MONDO:0003847","MONDO:0004335","MONDO:0045024","MONDO:0002516","MONDO:0004950","MONDO:0004993","MONDO:0023370","MONDO:0004298","MONDO:0000001","MONDO:0006181"],"children":["MONDO:0006226","MONDO:0007648","MONDO:0017790","MONDO:0100256"],"definition":"Hereditary gastric cancer refers to the occurrence of gastric cancer in a familial context and is described as two or more cases of gastric cancer in first or second degree relatives with at least one case diagnosed before the age of 50. Familial clustering is observed in 10% of all cases of gastric cancer, and includes hereditary diffuse gastric cancer (early onset diffuse-type gastric cancer), gastric adenocarcinoma and proximal polyposis of the stomach and familial intestinal gastric cancer (familial clustering of intestinal type gastric adenocarcinoma). Hereditary gastric cancer can also occur in other hereditary cancer syndromes such as Lynch syndrome, Li-Fraumeni syndrome, familial adenomatous polyposis and juvenile polyposis syndrome. [Orphanet:423776]","descendants":["MONDO:0100256","MONDO:0017790","MONDO:0007648","MONDO:0006226"],"label":"hereditary gastric cancer","mondo":"MONDO:0018502","parents":["MONDO:0003847","MONDO:0004950"],"synonym":{"exact":["hereditary cancer of stomach","hereditary gastric cancer"]},"xrefs":{"gard":["21758"],"medgen":["1843054"],"orphanet":["423776"],"umls":["C5680075"]}}},{"_id":"MONDO:0001060","_score":7.269791,"disease_ontology":{"_license":"https://github.com/DiseaseOntology/HumanDiseaseOntology/blob/master/DO_LICENSE.txt","ancestors":["DOID:14566","DOID:5517","DOID:305","DOID:3119","DOID:0050686","DOID:10534","DOID:4","DOID:76","DOID:77","DOID:7","DOID:0050687","DOID:162","DOID:3717","DOID:299"],"children":[],"def":"","descendants":[],"doid":"DOID:10541","name":"microinvasive gastric cancer","parents":["DOID:3717"],"synonyms":{"exact":["early gastric cancer","Surface gastric cancer"]},"xrefs":{"ncit":"C27131","snomedct_us_2023_03_01":"276809004","umls_cui":"C0349530"}},"disgenet":{"_license":"https://creativecommons.org/licenses/by/4.0/","genes_related_to_disease":[{"DPI":0.885,"DSI":0.429,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":174,"gene_name":"AFP","pubmed":[29121872],"score":0.01,"source":"BEFREE"},{"DPI":0.962,"DSI":0.373,"EI":1.0,"YearFinal":2016,"YearInitial":2014,"gene_id":324,"gene_name":"APC","pubmed":[27514024,24272205],"score":0.02,"source":"BEFREE"},{"DPI":0.808,"DSI":0.502,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":387,"gene_name":"RHOA","pubmed":[28624843],"score":0.01,"source":"BEFREE"},{"DPI":0.923,"DSI":0.344,"EI":1.0,"YearFinal":2014,"YearInitial":2014,"gene_id":595,"gene_name":"CCND1","pubmed":[25202078],"score":0.01,"source":"BEFREE"},{"DPI":0.423,"DSI":0.666,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":618,"gene_name":"BCYRN1","pubmed":[29039538],"score":0.01,"source":"BEFREE"},{"DPI":0.731,"DSI":0.459,"EI":1.0,"YearFinal":2008,"YearInitial":2008,"gene_id":864,"gene_name":"RUNX3","pubmed":[18097595],"score":0.01,"source":"BEFREE"},{"DPI":0.962,"DSI":0.363,"EI":1.0,"YearFinal":2019,"YearInitial":2016,"gene_id":960,"gene_name":"CD44","pubmed":[27923017,30913874,25779358],"score":0.03,"source":"BEFREE"},{"DPI":0.808,"DSI":0.401,"EI":1.0,"YearFinal":2010,"YearInitial":2010,"gene_id":999,"gene_name":"CDH1","pubmed":[20063069],"score":0.01,"source":"BEFREE"},{"DPI":0.769,"DSI":0.458,"EI":1.0,"YearFinal":2019,"YearInitial":2019,"gene_id":1045,"gene_name":"CDX2","pubmed":[31354341],"score":0.01,"source":"BEFREE"},{"DPI":0.846,"DSI":0.42,"EI":1.0,"YearFinal":2018,"YearInitial":2017,"gene_id":1048,"gene_name":"CEACAM5","pubmed":[29121872,29742692],"score":0.02,"source":"BEFREE"},{"DPI":0.731,"DSI":0.494,"EI":1.0,"YearFinal":2018,"YearInitial":2017,"gene_id":1084,"gene_name":"CEACAM3","pubmed":[29121872,29742692],"score":0.02,"source":"BEFREE"},{"DPI":0.769,"DSI":0.494,"EI":1.0,"YearFinal":2018,"YearInitial":2017,"gene_id":1087,"gene_name":"CEACAM7","pubmed":[29121872,29742692],"score":0.02,"source":"BEFREE"},{"DPI":0.808,"DSI":0.446,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":1268,"gene_name":"CNR1","pubmed":[27271924],"score":0.01,"source":"BEFREE"},{"DPI":0.846,"DSI":0.4,"EI":1.0,"YearFinal":2018,"YearInitial":2018,"gene_id":1351,"gene_name":"COX8A","pubmed":[30128004],"score":0.01,"source":"BEFREE"},{"DPI":0.615,"DSI":0.558,"EI":1.0,"YearFinal":2012,"YearInitial":2012,"gene_id":1365,"gene_name":"CLDN3","pubmed":[22290341],"score":0.01,"source":"BEFREE"},{"DPI":0.808,"DSI":0.494,"EI":1.0,"YearFinal":2012,"YearInitial":2012,"gene_id":1366,"gene_name":"CLDN7","pubmed":[22290341],"score":0.01,"source":"BEFREE"},{"DPI":0.846,"DSI":0.488,"EI":1.0,"YearFinal":2018,"YearInitial":2018,"gene_id":1371,"gene_name":"CPOX","pubmed":[29425880],"score":0.01,"source":"BEFREE"},{"DPI":0.923,"DSI":0.328,"EI":1.0,"YearFinal":2005,"YearInitial":2005,"gene_id":1636,"gene_name":"ACE","pubmed":[16365022],"score":0.01,"source":"BEFREE"},{"DPI":0.885,"DSI":0.426,"EI":1.0,"YearFinal":2019,"YearInitial":2019,"gene_id":1666,"gene_name":"DECR1","pubmed":[31370714],"score":0.01,"source":"BEFREE"},{"DPI":0.885,"DSI":0.295,"EI":1.0,"YearFinal":2015,"YearInitial":2015,"gene_id":1956,"gene_name":"EGFR","pubmed":[25593477],"score":0.01,"source":"BEFREE"},{"DPI":0.923,"DSI":0.328,"EI":1.0,"YearFinal":2018,"YearInitial":2015,"gene_id":2064,"gene_name":"ERBB2","pubmed":[30120594,25593477],"score":0.02,"source":"BEFREE"},{"DPI":0.615,"DSI":0.656,"EI":1.0,"YearFinal":2019,"YearInitial":2017,"gene_id":2098,"gene_name":"ESD","pubmed":[31382963,30725253,28378078,30298447],"score":0.04,"source":"BEFREE"},{"DPI":0.692,"DSI":0.588,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":2168,"gene_name":"FABP1","pubmed":[27884752],"score":0.01,"source":"BEFREE"},{"DPI":0.846,"DSI":0.474,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":2194,"gene_name":"FASN","pubmed":[27884752],"score":0.01,"source":"BEFREE"},{"DPI":0.808,"DSI":0.485,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":2520,"gene_name":"GAST","pubmed":[28072871],"score":0.01,"source":"BEFREE"},{"DPI":0.808,"DSI":0.489,"EI":1.0,"YearFinal":2019,"YearInitial":2019,"gene_id":2744,"gene_name":"GLS","pubmed":[30485682],"score":0.01,"source":"BEFREE"},{"DPI":0.577,"DSI":0.686,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":3004,"gene_name":"GZMM","pubmed":[28977792],"score":0.01,"source":"BEFREE"},{"DPI":0.885,"DSI":0.374,"EI":1.0,"YearFinal":2017,"YearInitial":2017,"gene_id":3082,"gene_name":"HGF","pubmed":[28595915],"score":0.01,"source":"BEFREE"},{"DPI":0.769,"DSI":0.476,"EI":1.0,"YearFinal":2015,"YearInitial":2015,"gene_id":3490,"gene_name":"IGFBP7","pubmed":[26043748],"score":0.01,"source":"BEFREE"},{"DPI":0.923,"DSI":0.373,"EI":1.0,"YearFinal":2004,"YearInitial":2004,"gene_id":3557,"gene_name":"IL1RN","pubmed":[15570075],"score":0.01,"source":"BEFREE"},{"DPI":0.962,"DSI":0.248,"EI":1.0,"YearFin...
curl --location --request GET 'https://zylalabs.com/api/4424/diseases+information+api/5437/disease?q=cancer' --header 'Authorization: Bearer YOUR_API_KEY'
Para utilizar este endpoint, debes especificar un ID de Mondo en el parámetro.
Por ejemplo: MONDO:0011361
Obtenrás este ID del endpoint de Enfermedad.
{"_id":"MONDO:0011361","_version":1,"ctd":{"omim":"603688","pathway_related_to_disease":[{"inference_gene_symbol":"EPHB2","kegg_pathway_id":"hsa04360","pathway_name":"Axon guidance","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Developmental Biology","react_pathway_id":"R-HSA-1266738","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPH-Ephrin signaling","react_pathway_id":"R-HSA-2682334","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"L1CAM interactions","react_pathway_id":"R-HSA-373760","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPHB-mediated forward signaling","react_pathway_id":"R-HSA-3928662","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Ephrin signaling","react_pathway_id":"R-HSA-3928664","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"EPH-ephrin mediated repulsion of cells","react_pathway_id":"R-HSA-3928665","source":"CTD"},{"inference_gene_symbol":"EPHB2","pathway_name":"Axon guidance","react_pathway_id":"R-HSA-422475","source":"CTD"}]},"disgenet":{"_license":"https://creativecommons.org/licenses/by/4.0/","genes_related_to_disease":[{"DPI":0.846,"DSI":0.374,"gene_id":2048,"gene_name":"EPHB2","score":0.4,"source":"CLINVAR"},{"DPI":0.846,"DSI":0.374,"gene_id":2048,"gene_name":"EPHB2","score":0.4,"source":"CTD_human"}],"variants_related_to_disease":[{"DSI":1.0,"chrom":"1","pos":22907980,"rsid":"rs121912582","score":0.7,"source":"CLINVAR"},{"DPI":0.08,"DSI":0.882,"chrom":"1","pos":22913757,"rsid":"rs76826147","score":0.7,"source":"CLINVAR"}],"xrefs":{"disease_name":"PROSTATE CANCER/BRAIN CANCER SUSCEPTIBILITY (finding)","mondo":"MONDO:0011361","omim":"603688","umls":"C1863600"}},"hpo":{"disease_name":"Prostate cancer/brain cancer susceptibility","omim":"603688","phenotype_related_to_disease":[{"biocuration":{"date":"2013-01-14","name":"HPO:skoehler"},"evidence":"IEA","hpo_id":"HP:0100006","omim_refs":"OMIM:603688","original_disease_id":"OMIM:603688"},{"biocuration":{"date":"2013-01-09","name":"HPO:skoehler"},"evidence":"IEA","hpo_id":"HP:0012125","omim_refs":"OMIM:603688","original_disease_id":"OMIM:603688"}]},"mondo":{"ancestors":["MONDO:0003847","MONDO:0020573","MONDO:0023370","MONDO:0021058","MONDO:0700096","MONDO:0002254","MONDO:0045024","MONDO:0042489","MONDO:0015356","MONDO:0000001"],"excluded_subClassOf":{"mondo":["MONDO:0008315"]},"has_material_basis_in_germline_mutation_in":{"http":["http://identifiers.org/hgnc/3393"]},"label":"prostate cancer/brain cancer susceptibility","mondo":"MONDO:0011361","parents":["MONDO:0015356"],"predisposes_towards":{"mondo":["MONDO:0001657"]},"synonym":{"exact":["prostate cancer/brain cancer susceptibility","prostate cancer/brain cancer susceptibility, somatic"],"related":["Capb","Pcbc"]},"xrefs":{"medgen":["400334"],"omim":["603688"],"umls":["C1863600"]}}}
curl --location --request GET 'https://zylalabs.com/api/4424/diseases+information+api/5439/disease+by+id&ID=Required' --header 'Authorization: Bearer YOUR_API_KEY'
Encabezado | Descripción |
---|---|
Autorización
|
[Requerido] Debería ser Bearer access_key . Consulta "Tu Clave de Acceso a la API" arriba cuando estés suscrito. |
Sin compromiso a largo plazo. Mejora, reduce o cancela en cualquier momento. La Prueba Gratuita incluye hasta 50 solicitudes.
La API de Información sobre Enfermedades proporciona datos e información estructurados sobre diversas enfermedades, incluidos los factores genéticos, los genes asociados, las manifestaciones clínicas y las vías relacionadas.
Zyla ofrece una amplia gama de métodos de integración para casi todos los lenguajes de programación. Puedes utilizar estos códigos para integrarlos en tu proyecto según lo necesites.
Hay diferentes planes para adaptarse a todos los gustos, incluyendo una prueba gratuita para un pequeño número de solicitudes, pero tu tarifa está limitada para evitar el abuso del servicio.
Esta API es esencial porque permite a los usuarios obtener información detallada y actualizada sobre una amplia gama de enfermedades, incluidos datos genéticos, genes asociados, variantes, datos clínicos y vías relevantes.
Para usar esta API, los usuarios deben indicar el nombre de una enfermedad.
El endpoint GET Disease devuelve una lista de enfermedades con genes asociados, variantes genéticas y fenotipos clínicos. El endpoint GET Disease by ID proporciona información detallada sobre una enfermedad específica, incluyendo las vías relacionadas con la enfermedad e interacciones de genes.
Los campos clave incluyen "_id" (identificador de enfermedad), "ctd" (datos relacionados con genes y vías), "omim" (ID de Herencia Mendeliana en Línea en Humanos) y "pathway_related_to_disease" (lista de vías vinculadas a la enfermedad).
Los datos de respuesta están estructurados en formato JSON, con un objeto de nivel superior que contiene metadatos (como "took" y "total") y un arreglo de "hits" que detalla la información de cada enfermedad, incluidos los genes y rutas asociados.
El endpoint GET Disease proporciona nombres de enfermedades, genes asociados y variantes genéticas. El endpoint GET Disease by ID ofrece detalles completos sobre una enfermedad específica, incluyendo vías, interacciones genéticas y datos clínicos.
El endpoint GET Enfermedad requiere el nombre de la enfermedad como parámetro, mientras que el endpoint GET Enfermedad por ID requiere un ID Mondo específico. Estos parámetros permiten a los usuarios personalizar sus consultas para obtener información específica.
Los usuarios pueden analizar los datos devueltos para identificar factores genéticos asociados con enfermedades, apoyar la toma de decisiones clínicas e informar sobre la investigación de los mecanismos de las enfermedades. El formato estructurado permite una fácil integración en aplicaciones.
Los datos se obtienen de bases de datos biomédicas de prestigio, incluyendo la Base de Datos de Toxicogenómica Comparativa (CTD) y la Herencia Mendeliana en Línea en el Hombre (OMIM), asegurando una alta precisión y fiabilidad.
Si la API devuelve resultados parciales o vacíos, los usuarios deben verificar la precisión de los parámetros de entrada. Además, considere usar términos de búsqueda más amplios o verificar nombres alternativos de enfermedades para mejorar la recuperación de resultados.
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To give you the opportunity to experience our APIs without any commitment, we offer a 7-day free trial that allows you to make up to 50 API calls at no cost. This trial can be used only once, so we recommend applying it to the API that interests you the most. While most of our APIs offer a free trial, some may not. The trial concludes after 7 days or once you've made 50 requests, whichever occurs first. If you reach the 50 request limit during the trial, you will need to "Start Your Paid Plan" to continue making requests. You can find the "Start Your Paid Plan" button in your profile under Subscription -> Choose the API you are subscribed to -> Pricing tab. Alternatively, if you don't cancel your subscription before the 7th day, your free trial will end, and your plan will automatically be billed, granting you access to all the API calls specified in your plan. Please keep this in mind to avoid unwanted charges.
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Nivel de Servicio:
100%
Tiempo de Respuesta:
1.986,42ms
Nivel de Servicio:
100%
Tiempo de Respuesta:
1.505,97ms
Nivel de Servicio:
100%
Tiempo de Respuesta:
458,46ms
Nivel de Servicio:
100%
Tiempo de Respuesta:
597,40ms
Nivel de Servicio:
100%
Tiempo de Respuesta:
452,69ms